基本信息
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 姓名:
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萬虎 |
出生年月: |
1984.10 |
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性别: |
男 |
碩/博導： |
博導 |
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民族: |
漢族 |
開設課程： |
農藥學概論、植物化學保護學、農藥學研究進展 |
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職稱: |
教授 |
研究方向： |
農藥毒理學、核酸農藥創制 |
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學位: |
理學博士 |
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聯系方式
電子郵件：huwan@mail.hzau.edu.cn
辦公地址：三綜B711 |
個人簡介
萬虎，男，1984年10月29日出生，江西九江人，博士，教授，博士研究生導師。主要從事農藥毒理及核酸農藥創制等研究。
（一）學習經曆
2002/09-2006/06 77779193永利官网獲農學學士學位
2006/09-2008/12 77779193永利官网獲農學碩士學位
2009/03-2013/02 韓國東亞大學生命資源科學學院獲理學博士學位
（二）工作經曆
2013/06 - 2017/12 77779193永利官网植物保護系 講 師
2018/01 - 至今 77779193永利官网植物保護系 副教授
（三）主要學術兼職
湖北省植物保護學會第十一屆理事會理事
中國植物保護學會第七屆青年工作委員會委員
科研項目
1. 國家自然科學基金，共生菌Wolbachia調控褐飛虱對氟啶蟲胺腈抗性的分子機制研究，項目年限：2021-2024，（主持） 2. 湖北省重點研發計劃，褐飛虱P450基因靶向性RNAi納米農藥創制，項目年限：2021-2023，（主持） 3. 湖北省自然科學基金，褐飛虱共生菌協同宿主解毒代謝機制研究，項目年限：2019-2020，（主持） 4. 國家自然科學基金，褐飛虱共生菌調控宿主解毒代謝基因細胞色素P450表達的機制研究，項目年限：2019-2022，（主持） 5. 77779193永利官网校自主創新基金，褐飛虱共生菌Wolbachia介導宿主解毒代謝機制研究，項目年限：2018-2020，（主持） 6. 湖北省青年英才開發計劃，項目年限：2017-2019，（主持） 7. 湖北省重大科技創新計劃，雙酰胺類殺蟲劑緩釋劑的制備及生物活性研究，項目年限：2016-2019，（參與） 8. 國家重點研發計劃，水稻化學農藥協同增效技術與産品研發，項目年限：2016-2020，（子課題主持） 9. 國家自然科學基金，褐飛虱對氟啶蟲胺腈早期抗性進化機理研究，項目年限：2016-2018，（主持） 10. 77779193永利官网自主創新基金，斜紋夜蛾過氧化物還原酶SlPrx5分子克隆及功能分析，項目年限：2014-2015，（主持） 11. 新進博士科研啟動專項，甜菜夜蛾谷胱甘肽轉移酶的分子特性研究，項目年限：2013-2014，（主持）
教學研究與教學改革 1. 2020年學院教改項目：77779193永利官网“課程思政”《農藥學概論》示範建設項目（主持） 2. 2019年校級教改項目：77779193永利官网全英文課程《農藥學研究進展》建設教改項目（主持） 3. 2018年校級教改項目：77779193永利官网第六批精品課程《植物化學保護學》在線開放課程建設（參與） 4. 2018年校級教改項目：77779193永利官网“思政課程”與“課程思政”《植物化學保護學》示範建設項目（參與） |
發明專利及獲獎情況
發明專利： 1. 何順，李建洪，萬虎，馬洪菊，遊紅，張小磊，高雲昊，沙黑拉什·拉馬贊. 一種納米二氧化矽接枝有機功能高分子有機磷殺蟲劑緩釋劑及其制備方法，專利号：ZL 201610191276.1 2. 何順，李建洪，萬虎，馬洪菊，高雲昊，沙黑拉什·拉馬贊，張小磊. 納米二氧化矽接枝有機功能高分子大環内酯類殺蟲劑緩釋劑及其制備方法，專利号：ZL 201610191303.5 3. 何順，李建洪，萬虎，遊紅，高雲昊，張小磊，廖遜. 一種納米二氧化矽接枝有機功能高分子雙酰胺類殺蟲劑緩釋劑及其制備方法，專利号：ZL 201610192026.X 4. 萬虎，韓甯甯，李建洪，陳子姝，黃國華. 快速測定囊泡病毒滴度的方法，專利号：ZL 201610522012.X 5. 朱福興，馬洪菊，萬虎，何順，馬偉華，楊中華. 一種複配殺菌劑及制備方法，專利号：ZL 201610807377.7 6. 萬虎，李建洪，高娃，遊紅.大腹園蛛絲氨酸蛋白酶抑制劑AvSPI基因及其編碼蛋白和應用，專利号：ZL 2013 1 0695392.3 主要獎勵： 1. 2020年度77779193永利官网優秀班主任 2. 2019年度77779193永利官网優秀碩士學位論文指導教師 3. 2019年度77779193永利官网“研究生就業工作貢獻獎” 4. 2016年度“湖北省青年英才開發計劃” 5. 湖北省第十一屆“挑戰杯”大學生課外學術科技作品競賽二等獎指導教師 6. 2016年度77779193永利官网教學質量優秀三等獎 7. 2015年度77779193永利官网教學質量優秀獎 8. 2014年度湖北省第十五屆自然科學優秀學術論文三等獎 9. 2014北京GRC籌備和組織工作特别嘉獎 10. 第一屆趙善歡獎學獎教基金優秀論文獎，2014，廣州，中國
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發表的論文及著作（*表示通訊作者，#表示共同作者）：
學術論文
1. Ren, Z., Zhang, Y., Cai, T., Mao, K., Xu, Y., Li, C., He, S., Li, J., Wan, H.*, 2021. Dynamics of Microbial Communities across the Life Stages of Nilaparvata lugens (Stål). Microbiol Ecol. In Press.
2. Zhang, Y., Cai, T., Ren, Z., Liu, Y., Yuan, M., Cai, Y., Yu, C., Shu, R., He, S., Li, J., Wong, A.C.N.*, Wan, H.*, 2021. Decline in symbiont-dependent host detoxification metabolism contributes to increased insecticide susceptibility of insects under high temperature. The ISME J. In Press.
3. Zhang, Y. #, Liu, C. #, Jin, R., Wang, Y., Cai, T., Ren, Z., Ma, K., He, S., Lee, K.S., Jin, B.R., Li, J., Wan, H.*, 2021. Dual oxidase-dependent reactive oxygen species are involved in the regulation of UGT overexpression-mediated clothianidin resistance in the brown planthopper, Nilaparvata lugens. Pest Manage. Sci. 77, 4159-4167.
4. Tang, T. #, Zhang, Y. #, Cai, T., Deng, X., Liu, C., Li, J., He, S., Li, J., Wan, H.*, 2021. Antibiotics increased host insecticide susceptibility via collapsed bacterial symbionts reducing detoxification metabolism in the brown planthopper, Nilaparvata lugens. J. Pest. Sci. 94, 757-767.
5. Mao, K., Ren, Z., Li, W., Cai, T., Qin, X., Wan, H., Jin, B.R., He, S.*, Li, J.*, 2021. Carboxylesterase genes in nitenpyram-resistant brown planthoppers, Nilaparvata lugens. Insect Sci. 28, 1049-1060.
6. Mao, K. #, Ren, Z. #, Li, W., Liu, C., Xu, P., He, S., Li, J., Wan, H.*, 2021. An insecticide resistance diagnostic kit for whitebacked planthopper Sogatella furcifera (Horvath). J. Pest. Sci. 94, 531-540.
7. Cai, T., Zhang, Y., Liu, Y., Deng, X., He, S., Li, J., Wan, H.*, 2021. Wolbachia enhances expression of NlCYP4CE1 in Nilaparvata lugens in response to imidacloprid stress. Insect Sci. 28, 355-362.
8. Gao, Y. #, Xiao Y. #, Mao, K., Qin, X., Zhang, Y., Li, D., Zhang, Y., Li, J., Wan, H.*, He, S.*, 2020. Thermoresponsive polymer-encapsulated hollow mesoporous silica nanoparticles and their application in insecticide delivery. Chem. Eng. J. 383, 123169.
9. 廖遜，萬虎，李建洪*，2019. 褐飛虱對殺蟲劑抗性研究進展. 農藥學學報. 21, 718-728.
10. 張雲骅，李建洪，萬虎*，2019. 昆蟲共生菌與宿主的解毒代謝關系研究進展. 農藥學學報. 21, 729-735.
11. Mao, K., Li, W., Liao, X., Liu, C., Qin, Y., Ren, Z., Qin, X., Wan, H., Sheng, F.*, Li, J.*, 2019. Dynamics of Insecticide Resistance in Different Geographical Populations of Chilo suppressalis (Lepidoptera: Crambidae) in China 2016-2018. J. Econ. Entomol. 112, 1866-1874.
12. Li, D. #, Zhang, Y. #, Li, W., Tang, T., Wan, H., You, H. *, Li, J. *, 2019. Fitness and evolution of insecticide resistance associated with gut symbionts in metaflumizone-resistant Plutella xylostella. Crop Prot. 124, 104869.
13. Liao, X., Mao, K., Ali, E., Jin, R., Li, Z., Li, W., Li, J., Wan, H.*, 2019. Inheritance and fitness costs of sulfoxaflor resistance in Nilaparvata lugens (Stål). Pest Manage. Sci. 75, 2981-2988.
14. Mao, K., Zhang, X., Ali, E., Liao, X., Jin, R., Ren, Z., Wan, H., Li, J.*, 2019. Characterization of nitenpyram resistance in Nilaparvata lugens (Stål). Pestic. Biochem. Physiol. 157, 26-30.
15. Mao, K. #, Jin, R. #, Li, W., Ren, Z., Qin, X., He, S., Li, J., Wan, H.*, 2019. The influence of temperature on the toxicity of insecticides to Nilaparvata lugens (Stål). Pestic. Biochem. Physiol. 156, 80-86.
16. 徐鵬飛，康廷浩，張 園，秦雪瑩，何 順，李建洪，萬 虎*，2019. 卵磷脂桶混助劑的特性及其在防治稻飛虱中對氟啶蟲胺腈的協同增效作用. 農藥學學報. 21, 227-232.
17. Jin, R., Mao, K., Liao, X., Xu, P., Li, Z., Ali, E., Wan, H., Li, J.*, 2019. Overexpression of CYP6ER1 associated with clothianidin resistance in Nilaparvata lugens (Stål). Pestic. Biochem. Physiol. 154, 39-45.
18. Liao, X., Jin, R., Zhang, X., Ali, E., Mao, K., Xu, P., Li, J., Wan, H.*, 2019. Characterization of sulfoxaflor resistance in the brown planthopper, Nilaparvata lugens (Stål). Pest Manage. Sci. 75, 1646-1654.
19. Liao, X., Ali, E., Li, W., He, B., Gong, P., Xu, P., Li, J., Wan, H.*, 2019. Sublethal effects of sulfoxaflor on the development and reproduction of the brown planthopper, Nilaparvata lugens (Stål). Crop Prot. 118, 6-14.
20. Xu, P., Shu, R., Gong, P., Li, W., Wan, H., Li, J.*, 2019. Sublethal and transgenerational effects of triflumezopyrim on the biological traits of the brown planthopper, Nilaparvata lugens (Stål) (Hemiptera: Delphacidae). Crop Prot. 117, 63-68.
21. Zhang, Y., Tang, T., Li, W., Cai, T., Li, J., Wan, H.*, 2018. Functional profiling of the gut microbiomes in two different populations of the brown planthopper, Nilaparvata lugens. J. Asia-Pac. Entomol. 21, 1309-1314.
22. Han, N., Chen, Z., Wan, H., Huang, G., Li, J.*, Jin, R.*, 2018. A rapid method for titration of ascovirus infectivity. J. Virol. Methods 255, 101-106.
23. Zhang, X., Mao, K., Liao, X., He, B., Jin, R., Tang, T., Wan, H., Li, J.*, 2018. Fitness cost of nitenpyram resistance in the brown planthopper Nilaparvata lugens. J. Pest. Sci. 91, 1145-1151.
24. Ali, E., Liao, X., Yang, P., Mao, K., Zhang, X., Shakeel, M., Salim, A., Wan, H.*, Li, J., 2017. Sublethal effects of buprofezin on development and reproduction in the white-backed planthopper, Sogatella furcifera (Hemiptera: Delphacidae). Sci. Rep. 7, 16913.
25. Zhang, Y., Ji, J., Zhao, X., Jin, R., Li, J., Wan, H.*, 2017. Expression, purification and enzymatic properties of a β-N-acetylhexosaminidase from brown planthopper, Nilaparvata lugens. J. Asia-Pac. Entomol. 20, 1340-1343.
26. Liao, X., Mao, K., Ali, E., Zhang, X., Wan, H.*, Li, J., 2017. Temporal variability and resistance correlation of sulfoxaflor susceptibility among Chinese populations of the brown planthopper Nilaparvata lugens (Stål). Crop Prot. 102, 141-146.
27. Zhang, X. #, Liao, X. #, Mao, K., Yang, P., Li, D., Ali, E., Wan, H., Li, J., 2017. Neonicotinoid insecticide resistance in the field populations of Sogatella furcifera (Horváth) in Central China from 2011 to 2015. J. Asia-Pac. Entomol. 20, 955-958.
28. Chen, Z.S., Han, N.N., Li, J.H., Huang, G.H., Wan, H.*, 2017. Selection of reference genes for expression analysis using RT-qPCR in the dissemination system of Heliothis virescens ascovirus 3 h (HvAV-3h). Sci. Rep. 7, 7045.
29. Shen, J., Li, D., Zhang, S., Zhu, X., Wan, H., Li, J., 2017. Fitness and inheritance of metaflumizone resistance in Plutella xylostella. Pestic. Biochem. Physiol. 139, 53-59.
30. Zhang, S. #, Zhang, X. #, Shen, J., Li, D., Wan, H., You, H., Li, J., 2017. Cross-resistance and biochemical mechanisms of resistance to indoxacarb in the diamondback moth, Plutella xylostella. Pestic. Biochem. Physiol. 140, 85-89.
31. Kang, T., Jin, R., Zhang, Y., Wan, H., Lee, K.S., Jin, B.R.*, Li, J.*, 2017. Functional characterization of the aspartic proteinase cathepsin D in the beet armyworm (Spodoptera exigua). Gene 617, 1-7.
32. Chen, Z.S., Han, N.N., Li, J.H., Wan, H., Huang, G.H.*, 2017. Selection and validation of reference genes for RT-qPCR analysis in Sf9 cell line infected by Heliothis virescens ascovirus 3h (HvAV-3h). J. Asia-Pac. Entomol. 20, 463-468.
33. Salim, A., Shakeel, M., Ji, J., Kang, T., Zhang, Y., Ali, E., Zhao, X., Lu, Y.*, Wan, H.*, Li, J., 2017. Cloning, expression, and functional analysis of two acetylcholinesterase genes in Spodoptera litura (Lepidoptera: Noctuidae). Comp. Biochem. Physiol. B. 206, 16-25.
34. Zhang, X., Liao, X., Mao, K., Yang, P., Li, D., Alia, E., Wan, H.*, Li, J., 2017. The role of detoxifying enzymes in field-evolved resistance to nitenpyram in the brown planthopper Nilaparvata lugens in China. Crop Prot. 94, 106-114.
35. 張小磊，廖遜，毛凱凱，李建洪，萬虎*，2016. 湖北稻區白背飛虱田間種群抗藥性監測. 昆蟲學報. 59, 1213-1221.
36. Liu, S., Xie, J., Cheng, J., Li, B., Chen, T., Fu, Y., Li, G., Wang, M., Jin, H., Wan, H., Jiang, D., 2016. Fungal DNA virus infects a mycophagous insect and utilizes it as a transmission vector. PNAS. 113, 12803-12808.
37. Xu, P., Han, N., Kang, T., Zhan, S., Lee, K.S., Jin, B.R., Li, J., Wan, H.*, 2016. SeGSTo, a novel glutathione S-transferase from the beet armyworm (Spodoptera exigua) involved in detoxification and oxidative stress. Cell Stress Chaperones. 21, 805-816.
38. Zhang, X., Liao, X., Mao, K., Zhang, K., Wan, H.*, Li, J.*, 2016. Insecticide resistance monitoring and correlation analysis of insecticides in field populations of the brown planthopper Nilaparvata lugens (stål) in China 2012–2014. Pestic. Biochem. Physiol. 132, 13-20.
39. Wan, H., Zhan, S., Xia, X., Xu, P., You, H., Jin, B.R.*, Li, J.*, 2016. Identification and functional characterization of an epsilon glutathione S-transferase from the beet armyworm (Spodoptera exigua). Pestic. Biochem. Physiol. 132, 81-88.
40. Zhang, Y., Zhao, X., Ji, J., Kang, T., Li, J., Wan, H.*, 2016. Molecular cloning and characterization of a phenylalanine hydroxylase from the common cutworm Spodoptera litura. J. Asia-Pac. Entomol. 19, 365-370.
41. Wan, H., Zhang, Y., Zhao, X., Ji, J., You, H., Li, J.*, 2015. Enhancing the insecticidal activity of recombinant baculovirus by expressing a growth-blocking peptide from the beet armyworm Spodoptera exigua. J. Asia-Pac. Entomol. 18, 535-539.
42. Shakeel, M., Zhu, X., Kang, T., Wan, H., Li, J.*, 2015. Selection and evaluation of reference genes for quantitative gene expression studies in cotton bollworm, Helicoverpa armigera (Lepidoptera: Noctuidae). J. Asia-Pac. Entomol. 18, 123-130.
43. Kang, T. #, Wan, H. #, Zhang, Y., Shakeel, M., Lu, Y., You, H., Lee, K.S., Jin, B.R.*, Li, J.*, 2015. Comparative study of two thioredoxins from common cutworm (Spodoptera litura): cloning, expression, and functional characterization. Comp. Biochem. Physiol. B. 182, 47-54.)
44. Wan, H., Kang, T., Kim, B.Y., Lee, K.S., Li, J., Jin, B.R.*, 2015. AvCystatin, a novel cysteine protease inhibitor from spider (Araneus ventricosus) venom. J. Asia-Pac. Entomol. 18, 13-18.
45. Wan, H. #, Kang, T. #, Zhan, S., You, H., Zhu, F., Lee, K.S., Zhao, H., Jin, B.R.*, Li, J.*, 2014. Peroxiredoxin 5 from common cutworm (Spodoptera litura) acts as a potent antioxidant enzyme. Comp. Biochem. Physiol. B. 175, 53-61.
46. Yuan, M., Lu, Y., Zhu, X., Wan, H., Shakeel, M., Zhan, S., Jin B.R., Li, J.*, 2014. Selection and Evaluation of Potential Reference Genes for Gene Expression Analysis in the Brown Planthopper, Nilaparvata lugens (Hemiptera: Delphacidae) Using Reverse-Transcription Quantitative PCR. PLoS One. 9, e86503.
47. Zou, F.M., Lee, K.S., Wan, H., Gui, Z.Z., Jin, B.R.*, 2014. Morphological abnormalities and lethality in silkworm (Bombyx mori) larvae treated with high concentrations of insect growth-blocking peptide. J. Asia-Pac. Entomol. 17, 93-97.
48. Wan, H. #, Kim, B.Y. #, Lee, K.S., Yoon, H.J., Lee, K.Y., Jin, B.R.*, 2014. A bumblebee (Bombus ignitus) venom serine protease inhibitor that acts as a microbial serine protease inhibitor. Comp. Biochem. Physiol. B. 167, 59-64. (Co-first author)
49. Kim, B.Y., Lee, K.S., Zou, F.M., Wan, H., Choi, Y.S., Yoon, H.J., Kwon, H.W., Je, Y.H., Jin, B.R.*, 2013. Antimicrobial activity of a honeybee (Apis cerana) venom Kazal-type serine protease inhibitor. Toxicon 76, 110-117.
50. Wan, H., Lee, K.S., Kim, B.Y., Yuan, M., Zhan, S., Lu, Y., You, H., Li, J.*, Jin, B.R.*, 2013. Developmental regulation and antifungal activity of a growth-blocking peptide from the beet armyworm Spodoptera exigua. Dev. Comp. Immunol. 41, 240-247.
51. Lu, Y., Yuan, M., Gao, X., Kang, T., Zhan, S., Wan, H., Li, J.*, 2013. Identification and validation of reference genes for gene expression analysis using quantitative PCR in Spodoptera litura (Lepidoptera: Noctuidae). PLoS ONE 8, e68059.
52. Wan, H., Lee, K.S., Kim, B.Y., Yuan, M., Zhan, S., You, H., Li, J.*, Jin, B.R.*, 2013. A spider (Araneus ventricosus) chymotrypsin inhibitor that acts as an elastase inhibitor and a microbial serine protease inhibitor. Comp. Biochem. Physiol. B. 165, 36-41.
53. Wan, H., Lee, K.S., Kim, B.Y., Zou, F.M., Yoon, H.J., Je, Y.H., Li, J., Jin, B.R.*, 2013. A spider-derived Kunitz-type serine protease inhibitor that acts as a plasmin inhibitor and an elastase inhibitor. PLoS ONE 8, e53343.
54. Wan, H., Lee, K.S., Choo, Y.M., Je, Y.H., Li, J., Jin, B.R.*, 2013. Molecular cloning and characterization of two peptide toxins from the spider Araneus ventricosus. J. Asia-Pac. Entomol. 16, 81-86.
55. Kim, B.Y., Lee, K.S., Wan, H., Zou, F.M., Choi, Y.S., Yoon, H.J., Kwon, H.W., Je, Y.H., Jin, B.R.*, 2013. Anti-elastolytic activity of a honeybee (Apis cerana) chymotrypsin inhibitor. Biochem. Biophys. Res. Commun. 430, 144-149.
56. Wan, H., Yuan, M., You, H., Li, J.*, Jin, B.R.*, 2012 Molecular cloning and characterization of a diapause-specific peptide in the beet armyworm, Spodoptera exigua. J. Asia-Pac. Entomol. 15, 369-373.
57. Choo, Y.M., Lee, K.S., Yoon, H.J., Qiu, Y., Wan, H., Sohn, M.R., Sohn, H.D., Jin, B.R.*, 2012. Antifibrinolytic role of a bee venom serine protease inhibitor that acts as a plasmin inhibitor. PLoS ONE 7, e32269.
58. Kim, B.Y., Hui, W.L., Lee, K.S., Wan, H., Yoon, H.J., Gui, Z.Z., Chen, S., Jin, B.R.*, 2011. Molecular cloning and oxidative stress response of a sigma-class glutathione S-transferase of the bumblebee Bombus ignitus. Comp. Biochem. Physiol. B. 158, 83-89.
59. You, H. #, Wan, H. #, Li, J., Jin, B.R.*, 2010. Molecular cloning and characterization of a short peptidoglycan recognition protein (PGRP-S) with antibacterial activity from the bumblebee Bombus ignitus. Dev. Comp. Immunol. 34, 977-985.
