基本信息
小麥産量遺傳學，作物調控組學
2002.09-2006.06 77779193永利官网，生物科學，學士
2006.09-2012.12 77779193永利官网，遺傳學，博士
2013.03-2017.05 德國波茨坦大學, 博士後
2017.06-2019.03 德國洪堡大學, 博士後
2019.03 至今 77779193永利官网, 教 授
本人過去十多年主要圍繞植物花期的遺傳基礎和花（序）的發育調控開展研究。在研究中結合經典遺傳學、分子生物學、調控組學等手段，先後克隆了2個控制水稻開花期及穗大小的主效基因；并從基因的轉錄調控、染色質修飾和活性等多個層面研究了植物花發育過程中的調控機制。相關研究結果發表在Molecular Plant、Cell Research、New Phytologist、Nature Plants及Nature Communications等雜志上。2019年3月入職77779193永利官网，從事小麥産量性狀形成的遺傳及分子調控基礎的研究。本課題組将充分利用在模式植物拟南芥和水稻中積累的經驗、知識以及相關技術體系，圍繞着小麥開花期及穗發育的調控網絡以及小麥多倍化的調控生物學基礎等問題開展研究工作。
研究論文：(#,共同第一作者；*，通訊作者)
1. Wenhao Yan#, Dijun Chen#, Julia Schumacher, Diego Durantini, Julia Engelhorn, Ming Chen, Christel Carles, and Kerstin Kaufmann. Dynamic control of enhancer activity drives stage-specific gene expression during flower morphogenesis. Nature Communications, accepted.
2. Dijun Chen#, Wenhao Yan#, Liang-Yu Fu and Kerstin Kaufmann*. Architecture of gene regulatory networks controlling flower development in Arabidopsis thaliana. Nature Communications, 2018, 9:4534.
3. Wenhao Yan#*, Dijun Chen#, Cezary Smaczniak, Engelhorn Julia, Haiyang Liu, Wenjing Yang, Alexander Graf, Christel Carles, Dao-Xiu Zhou, and Kerstin Kaufmann*. Dynamic and spatial restriction of polycomb activity by plant histone demethylases. Nature Plants, 2018, 4: 681–689.
4. Julia Schumacher, Kerstin Kaufmann, and Wenhao Yan*. Multiplexed guideRNA-expression to efficiently mutagenize multiple loci in Arabidopsis by CRISPR-Cas9. Bio-protocol, 2017, e2166.
5. Wenhao Yan*, Dijun Chen and Kerstin Kaufmann*. Efficient multiplex mutagenesis by RNA-guided Cas9 and its use in the characterization of regulatory elements in the AGAMOUS gene. Plant Methods, 2016, 12: 23
6. Wenhao Yan, Dijun Chen and Kerstin Kaufmann*. Molecular mechanisms of floral organ specification by MADS domain proteins. Current Opinion in Plant Biology, 2016, 29:154–162
7. Jia Zhang#, Xiangchun Zhou#, Wenhao Yan#, Zhanyi Zhang, Li Lu, Zhongmin Han, Hu Zhao, Haiyang Liu, Pan Song, Yong Hu, Guojing Shen, Qin He, Sibin Guo, Guoqing Gao, Gongwei Wang and Yongzhong Xing*. Combinations of the Ghd7, Ghd8 and Hd1 genes largely define the ecogeographical adaptation and yield potential of cultivated rice. New Phytologist, 2015, 208: 1056-1066
8. Wenhao Yan#, Haiyang Liu#, Xiangchun Zhou, Qiuping Li, Jia Zhang, Li Lu, Touming Liu, Haijun Liu, Chengjun Zhang, Zhanyi Zhang, Guojing Shen, Wen Yao, Huaxia Chen, Sibin Yu, Weibo Xie, Yongzhong Xing*. Natural variation in Ghd7.1 plays an important role in grain yield and adaptation in rice. Cell Research, 2013, 23: 969-971.
9. Li Lu#, Wenhao Yan#, Weiya Xue, Di Shao, Yongzhong Xing*. Evolution and association analysis of Ghd7 in rice. Plos one, 2011, 7:e34021.
10. Wenhao Yan#, Peng Wang#, Huaxia Chen, Hongju Zhou, Qiuping Li, Chongrong Wang, Zehong Ding,Yushan Zhang, Sibin Yu*, Yongzhong Xing* and Qifa Zhang. A major QTL, Ghd8, plays pleiotropic roles in regulating grain productivity, plant height, and heading date in rice. Molecular Plant, 2011, 4: 319-330.
參編書籍：
Wenhao Yan, Zhongmin Han, and Yongzhong Xing*. Molecular diagnostics in rice (Oryza sativa). Chapter 20 of Diagnostics in Plant Breeding, 2013, pp 443-465
